NexGard Chew for Dogs, 24.1-60 lbs, (Purple Box)

NexGard (afoxolaner) contains afoxolaner which is absorbed into the bloodstream after ingestion. When fleas and ticks ingest blood containing afoxolaner, it causes hyperexcitation and death in these parasites. Dogs and puppies 8 weeks of age and older weighing 4 pounds of body weight or greater. Do not use on cats.

Afoxolaner is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Use with caution in dogs with a history of seizures or neurologic disorders. The safe use of NexGard (afoxolaner) in breeding, pregnant or lactating dogs has not been evaluated.

In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, nonsteroidal anti-inflammatory drugs (NSAIDs), anesthetics, and antihistamines. No adverse reactions were observed from the concomitant use of NexGard with other medications. For specific questions about your dog, we recommend that you consult with your veterinarian.

NexGard (afoxolaner) is for use in dogs only. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, contact your veterinarian or refer to the full prescribing information.